
The Urgency of Infection Management
In the UK each year, antimicrobial resistance (AMR) and sepsis are associated with over 50,000 deaths. In 2019, 87,500 deaths involved a bacterial infection. Treating AMR infections alone already costs the NHS, just in England, an estimated £180 million per year.
Infection and AMR are some of the greatest existential threats to our healthcare system in the present day. The creation of a ‘clean’ environment is the prerequisite for the effective delivery of all modern healthcare interventions and people need assurance that by being in a healthcare setting they will not contract further illness, let alone one that cannot be treated. Yet it is estimated that around 300,000 people a year in England acquire a healthcare associated infection (HCAI) during contact with the NHS, the use of antibiotics in hospitals is increasing and antibiotic resistance was present in 11 percent of infections in the UK (in 2019).
In England alone, data show that more than 1.7 million hospital episodes of care annually are precipitated or complicated by a bacterial infection requiring antibiotics. Although the risk of acquiring infection with resistant organisms is lower outside hospitals, it is important to note that a majority of people with serious infection and sepsis (approximately 80%) contract the causative infection in the community. Prevention here remains important, but at present vaccination can only prevent a minority of infections. In 2020, it was reported that 80% of UK antibiotic prescribing occurs in the community, the vast majority in primary care.
While the status quo of infection management is not working, the mortality and burden of infection will only increase. The Infection Management Coalition (IMC) exists to deploy the expertise of its membership to work with government to improve infection management processes for the benefit of patients and the whole of society.
2.4% increase
Total antibiotic consumption also increased by 2.4% between 2022 and 2023.³
35,200 deaths
Estimated that in the UK AMR is associated with 35,200 deaths each year, including 7,600 of which it is the direct cause.²
£2.7 billion
Healthcare associated infections were estimated to cost the NHS £2.7 billion - almost entirely attributed to costs associated with patient management.¹
only 7
By January 2024, only 7 of the 128 commitments in the AMR National Action Plan 19-24 had been completed.⁴
1. NICE CKS, Healthcare-associated infections (June 2024). Online: Prevalence | Background information | Healthcare-associated infections | CKS | NICE 2. NAO, Investigation into how government is addressing antimicrobial resistance (26 February 2025) 3. UKHSA, Infectious diseases impacting England: 2025 report. Online: Infectious diseases impacting England, 2025 report 4. National Audit Office analysis of Antimicrobial Resistance Delivery Board data, referenced in NAO, Investigation into how government is addressing antimicrobial resistance (26 February 2025)